MOODREAL^®

For relaxation, positive mood and emotional balance

MOODREAL^® is a new natural and powerful mood ingredient. Its mechanism of action has been proven to substantiate this mood activity through the inhibition of the reuptake of Serotonin.

MOODREAL^® is the replica of the saffron extracts that have shown, in published human clinical studies, the ability to fight against sad mood more effectively than Placebo.

Powerful Claims

In Europe, great possible Health Claims confirm its positioning in enabling the following communication:

Contributes to emotional balance

Helps to support relaxation

Helps to maintain a positive mood

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HIGHLIGHTS

MOODREAL^® matches the science published for mood behavior: Sargol vintage stigmas, a process that preserves its active ingredients, actives >2% safranal.
MOODREAL^® is usable in dietary supplements, has no side effects, and is successfully used by several thousand satisfied clients.
MOODREAL^® is water soluble thus enabling the development of various beverages and traditional presentations (tablets, capsules, …)

MOODREAL^® mechanism of action has been proven to substantiate this mood activity through the inhibition of the reuptake of Serotonin.

Serotonin is one of the neurotransmitters that influence mood and anxiety. After being produced, most Serotonin is degraded or reuptake in our brain…not leading to a sufficient quantity to lead to its activities after receptor binding. A serotonin reuptake inhibitor (SRI) acts as an inhibitor for the reuptake of the neurotransmitter serotonin (5-hydroxytryptamine (5-HT) by blocking the action of the serotonin transporter (SERT).

This in turn leads to increased extracellular concentrations of serotonin and, therefore, an increase in serotonergic neurotransmission. SRIs are commonly used to overcome anxiety and sadness.

For those willing to BEAR A POSITIVE MOOD

MOODREAL^® is the replica of the saffron extracts that have shown, in published human clinical studies, the ability to fight against sad mood more effectively than Placebo.

CLINICAL STUDY vs PLACEBO

Parameters

6 weeks

40 adults

Depression scoring

>18 Echelle Hamilton (HAM-D 17)

Groups

A: 15mgX2j ext. safran.>2% safranal

B: Placebo

Results

More efficient than placebo (p<0,001)

Akhondzadeh S. and Al., 2005 Phytother Res Vol 19, 2:148-51

Figure 1 Mean ± SEM scores of two groups of patients on the Hamilton Depression Rating Scale. ns = non-significant, ** = P < 0.01 and *** = P < 0.001. The horizontal symbols (** and ***) were used to express statistical significance versus their respective baseline value and ns symbols are for between group comparisons.