Nutraceuticals
Patented and clinically supported extract for weight management (Crocus Sativus L., Saffron)
Bioactives standardisation:
- Safranal ≥ 0.34% UV/VIS
Obesity is an increasingly worldwide problem
Generates satiety and less desire for carbs & craving
Inhibits Serotonin Reuptake
Patented and clinically supported extract (Crocus Sativus, Saffron)
Standardised extract from a known and safe natural source
Mechanism of Action(1)
Serotonin Reuptake Inhibitor (SRI)
Augmentation of brain serotonin inhibits food intake, while depletion of brain serotonin promotes hyperphagia and weight gain.
- Inhibits Serotonin Reuptake
- Generates satiety and less desire for carbs & cravings
SATIEREAL® has its own unique capacity of a Serotonin Reuptake Inhibitor (SRI):
- Improves emotional behaviour
- Exerts a satiating effect
- Decreases compulsive snacking leading to weight loss
Snacking is mostly due to low serotonin levels, a neurotransmitter that influences appetite.
Pilot Clinical Study(2)
Randomised – Double blinded – Placebo controlled
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16 women aged 46-61 years old with a tendency of non-pathological reflex (stress-related) polyphagia
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4 weeks
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Selection: Healthy slightly overweight women (22Randomisation in two Parallel Groups + Dietetic Advices: Group 1 (N=8) placebo, Group 2 (N=8)Half took 2 x 88.25 mg soft-gel capsules/day (breakfast & lunch), half took the placebo
Pilot Clinical Study Results
87.5% of women receiving SATIEREAL® stated that they:
- Decreased food intake
- Decreased hunger sensation
Compared to 0% of women receiving placebo
SATIEREAL® induced:
- Weight loss
- Fat mass loss
- Lean mass maintenance
SATIEREAL® consumption produced a significant reduction in hunger before lunch (*p < 0.05).
SATIEREAL® demonstrated its ability to positively affect the food intake (*p < 0.05).
Clinical Study(3)
Prospective, randomised, double-blind, placebo – controlled study:
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60 volunteers
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8 weeks
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Half took 2 x 88.25 mg soft-gel capsules/day, and half took the placebo
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Inclusion criteria: healthy, mildly overweight women (25
Clinical Study Results
- 84% decrease in appetite*
- 78% reduced sugar cravings*
- 55% decrease in snacking events*
- 69% decreased hunger*
*p<0.05 compared to placebo
- SATIEREAL® caused a significantly greater body weight reduction than placebo (**p < 0.01).
- The mean snacking frequency was significantly reduced in the SATIEREAL® group vs the placebo group (*p < 0.05).
- SATIEREAL® produces a reduction of snacking and creates a satiating effect that could contribute to body weight loss (up to 4.9 kgs).
- SATIEREAL® has demonstrated its ability to help reduce snacking frequency with consequent weight loss due to craving control.
Aplicactions
Functional foods
Bars
Shakes
Beverages
Confectionary
Powders
Snacks diet products
Supplements
Meal replacements
Sources
- (1) Namkung, J. et al. Mol. Cells, 2015, 38(12), 1023-1028
- (2) Internal study
- (3) Gout et al, Nutrition Research 2010, 30, 305-313
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