Nutraceuticals
A patented exclusive blend of botanical extracts that stimulates natural body drain functions and body detoxification

Mechanism of Action

- Inhibits Na+ reabsorption(1) in the proximal tubule leading to diuresis enhancement (caffeine).
- Blocks adenosine A1 receptor(2,3,4) mediated vasoconstriction leading to increase of renal blood flow & enhancing filtration rate (guarana).
- Increase Ca2+ uptake(5) leading via ATPAse Ca2+/Na+ pump to a higher release of Na+ in urine enhancing diuresis (dandelion).
- Inhibitis neutral endopeptidase(6) which increase natriuretic peptides concentrations that enhance natriuresis & diuresis (goldenrod)

Clinical Study
Randomised – Double blinded – Placebo controlled
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87 women aged between 20 and 50 years oldñl>
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28 daysñl>
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Volunteers were slightly overweight (BMI 25-28 kg/m2)ñl>
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Randomisation: divided into 3 groupsñl>
Group 1 (N = 28): Elimreal tablet + Placebo drink
Group 2 (N = 31): Placebo tablet + Elimreal drink
Group 3 (N = 28): Placebo tablet + Placebo drink
ELIMREAL® dosage = 805 mg/day for everyone
Number of urinations
Urination volume
Sodium elimination
Number of urinations per day
The variation in the number of urinations per day compared to the placebo was 60.4% higher in the tablets group and 82% higher in the beverages group.
24-hour urination volume
The variation in the urination volume in 24 hours compared to the placebo was 157% higher in the tablets group and 278% higher in the beverages group.
Sodium elimination in the 24-hour urine period
Group 1 demonstrated a 10.69% increase of sodium elimination per day (tablet), Group 2 an 8.78% increase (beverage), Group 3 a 15.97% decrease (placebo).
Clinical Study Results
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Increase in number of urinations per day, reported by 61% of volunteers.ñl>
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Increase in urine volume, reported by 58.3% of volunteers.ñl>
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Significant increase to the number of micturition's compared to D0.ñl>
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Increase of 24-hour urine volume.ñl>
Applications

Beverages

Bars

Supplements

Powder sticks
Sources
- (1) Zhang, Y. et al. J Sci Med Sport, 2015, 18(5), 569-74;
- (2) Rieg, T. et al. J Pharmacol Exp Ther, 2005, 313(1), 403–409;
- (3) Kurkin, V.A. et al. Science and Innovations in Medicine, 2021, 6(4), 68-72;
- (4)Jacobson, K.A. et al. Adv Exp Med Biol, 2002, 505, 163-71
- (5)Gerbino, A. et al. Int J Mol Sci, 2018,19(4), 1112;
- (6)Melzig, M. F. et al. Zeitschrift für Phytotherapie, 2000, 21(4), 193-196;
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