Nutraceuticals
Formula of plant extracts designed to stimulate natural body drain functions
Prevalence of Oedema is significant worldwide and it can be a symptom of an underlying medical condition.
Standardised extracts from known and safe natural sources
Perceived effectiveness of weight loss
Increase in sodium elimination through urine within 24 hours
Increase in number of urinations per day
Mechanism of Action
- Inhibits Na+ reabsorption in the proximal tubule leading to diuresis enhancement (caffeine).
- Blocks adenosine A1 receptor mediated vasoconstriction leading to increase of renal blood flow & enhancing filtration rate (guarana).
- Increase Ca2+ uptake leading via ATPAse Ca2+/Na+ pump to a higher release of Na+ in urine enhancing diuresis (dandelion).
- Inhibitis neutral endopeptidase which increase natriuretic peptides concentrations that enhance natriuresis & diuresis (goldenrod)
Clinical Study
Randomised – Double blinded – Placebo controlled
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87 women aged between 20 and 50 years old
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28 days
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Volunteers were slightly overweight (BMI 25-28 kg/m2)
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Randomisation: divided into 3 groups
Group 1 (N = 28): Elimreal tablet + Placebo drink
Group 2 (N = 31): Placebo tablet + Elimreal drink
Group 3 (N = 28): Placebo tablet + Placebo drink
ELIMREAL® dosage = 805 mg/day for everyone
Number of urinations
Urination volume
Eliminación de sodio
Number of urinations per day
The variation in the number of urinations per day compared to the placebo was 60.4% higher in the tablets group and 82% higher in the beverages group.
24-hour urination volume
The variation in the urination volume in 24 hours compared to the placebo was 157% higher in the tablets group and 278% higher in the beverages group.
Sodium elimination in the 24-hour urine period
Group 1 demonstrated a 10.69% increase of sodium elimination per day (tablet), Group 2 an 8.78% increase (beverage), Group 3 a 15.97% decrease (placebo).
Clinical Study Results
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Increase in number of urinations per day, reported by 61% of volunteers.
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Increase in urine volume, reported by 58.3% of volunteers.
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Significant increase to the number of micturition's compared to D0.
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Increase of 24-hour urine volume.
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Significant increase in sodium elimination through urine within 24-hour, which indicated a realdiuretic effect.
Applications
Beverages
Bars
Supplements
Powder sticks
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